Virtual-Integrated Twin for Autonomous Lifesaving (VITAL)

Agency: DEPT OF DEFENSE
State: Federal
Type of Government: Federal
FSC Category:
  • A - Research and development
NAICS Category:
  • 541714 - Research and Development in Biotechnology (except Nanobiotechnology)
Posted Date: Apr 21, 2026
Due Date: Jun 25, 2026
Solicitation No: DARPA-PS-26-26
Original Source: Please Login to View Page
Contact information: Please Login to View Page
Bid Documents: Please Login to View Page

Description

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Virtual-Integrated Twin for Autonomous Lifesaving (VITAL)
Active
Contract Opportunity
Notice ID
DARPA-PS-26-26
Related Notice
Department/Ind. Agency
DEPT OF DEFENSE
Sub-tier
DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)
Office
DEF ADVANCED RESEARCH PROJECTS AGCY
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General Information View Changes
  • Contract Opportunity Type: Solicitation (Updated)
  • Updated Published Date: Apr 21, 2026 12:07 pm EDT
  • Original Published Date: Apr 09, 2026 05:07 pm EDT
  • Updated Date Offers Due: Jun 25, 2026 04:00 pm EDT
  • Original Date Offers Due: Jun 25, 2026 04:00 pm EDT
  • Inactive Policy: Manual
  • Updated Inactive Date: Jul 25, 2026
  • Original Inactive Date: Jul 25, 2026
  • Initiative:
    • None
Classification
  • Original Set Aside:
  • Product Service Code: AC12 - NATIONAL DEFENSE R&D SERVICES; DEPARTMENT OF DEFENSE - MILITARY; APPLIED RESEARCH
  • NAICS Code:
    • 541714 - Research and Development in Biotechnology (except Nanobiotechnology)
  • Place of Performance:
Description View Changes
UPDATE: The purpose of Amendment 1 to DARPA-PS-26-26, the Virtual-Integrated Twin for Autonomous Lifesaving (VITAL) Program Solicitation (PS), is to clarify the proposal abstract questions deadline and the 7-page proposal abstract section requirements.

The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative approaches to address challenges in developing continuously updating digital twin models of the cardiovascular system that combine patient data with biological physics to simulate in real time possible interventions and to predict their outcomes before actual intervention on a patient. The VITAL program will establish a foundation for causal, prediction-driven decision support in medicine, enabling clinicians and future autonomous systems to evaluate treatment options before they are applied. By defining when mechanistic digital twins, reduced-order models, and data-driven inference are reliable and actionable, VITAL will shift medical care from reactive assessment to anticipatory intervention. This capability has the potential to improve outcomes across acute, chronic, and emergent clinical settings.
Attachments/Links
Contact Information
Contracting Office Address
  • 675 NORTH RANDOLPH STREET
  • ARLINGTON , VA 222032114
  • USA
Primary Point of Contact
Secondary Point of Contact


History

Related Document

Apr 9, 2026[Solicitation (Original)] Virtual-Integrated Twin for Autonomous Lifesaving (VITAL)
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