Treating Hereditary Rare Diseases With In Vivo Precision Genetic Medicines (THRIVE)

Agency: HEALTH AND HUMAN SERVICES, DEPARTMENT OF
State: District of Columbia
Type of Government: Federal
FSC Category:
  • A - Research and development
NAICS Category:
  • 541714 - Research and Development in Biotechnology (except Nanobiotechnology)
Set Aside: No Set aside used
Posted Date: Oct 9, 2025
Due Date: Dec 19, 2025
Solicitation No: ARPA-H-SOL-25-122
Original Source: Please Login to View Page
Contact information: Please Login to View Page
Bid Documents: Please Login to View Page

Description

Follow
Treating Hereditary Rare Diseases With In Vivo Precision Genetic Medicines (THRIVE)
Active
Contract Opportunity
Notice ID
ARPA-H-SOL-25-122
Related Notice
ARPA-H-SN-25-131
Department/Ind. Agency
HEALTH AND HUMAN SERVICES, DEPARTMENT OF
Sub-tier
NATIONAL INSTITUTES OF HEALTH
Office
ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)
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General Information View Changes
  • Contract Opportunity Type: Solicitation (Updated)
  • Updated Published Date: Oct 09, 2025 11:25 am EDT
  • Original Published Date: Sep 25, 2025 09:15 am EDT
  • Updated Date Offers Due: Dec 19, 2025 11:59 pm EST
  • Original Date Offers Due: Dec 19, 2025 11:59 pm EST
  • Inactive Policy: 15 days after date offers due
  • Updated Inactive Date: Jan 03, 2026
  • Original Inactive Date: Jan 03, 2026
  • Initiative:
    • None
Classification
  • Original Set Aside: No Set aside used
  • Product Service Code: AN13 - HEALTH R&D SERVICES; HEALTH CARE SERVICES; EXPERIMENTAL DEVELOPMENT
  • NAICS Code:
    • 541714 - Research and Development in Biotechnology (except Nanobiotechnology)
  • Place of Performance:
    Washington , DC 20005
    USA
Description View Changes

Amendment 1: Added the Frequently Asked Questions (FAQ) to the list of attachments.



The Advanced Research Projects Agency for Health (ARPA-H) Treating Hereditary Rare diseases with In Vivo precision genetic mEdicines (THRIVE) program envisions a future where patients can opt for one-time therapeutic interventions designed to slow, reverse, or cure disease, harnessing revolutionary technologies and a rapidly evolving understanding of the genetic underpinnings of the biological processes that lead to disease.



Interested parties are invited to review the attached THRIVE Innovative Solutions Opening (ISO) ARPA-H -SOL-25-122.

For detailed information regarding Proposers' Day review Special Notice (SN) ARPA-H-SN-25-131.



Solution summaries are due October 31, 2025, 11:59 PM ET.



For more information about THRIVE, please visit:https://arpa-h.gov/explore-funding/programs/thrive




Attachments/Links
Contact Information
Contracting Office Address
  • 1301 K Street NW Suite 1200 West
  • Washington , DC 20005
  • USA
Primary Point of Contact
Secondary Point of Contact


History

Related Document

Sep 25, 2025[Solicitation (Updated)] Treating Hereditary Rare Diseases With In Vivo Precision Genetic Medicines (THRIVE)
Oct 17, 2025[Solicitation (Updated)] Treating Hereditary Rare Diseases With In Vivo Precision Genetic Medicines (THRIVE)
Oct 27, 2025[Solicitation (Updated)] Treating Hereditary Rare Diseases With In Vivo Precision Genetic Medicines (THRIVE)
Nov 15, 2025[Solicitation (Updated)] Treating Hereditary Rare Diseases With In Vivo Precision Genetic Medicines (THRIVE)
Dec 2, 2025[Solicitation (Updated)] Treating Hereditary Rare Diseases With In Vivo Precision Genetic Medicines (THRIVE)
Dec 15, 2025[Solicitation (Updated)] Treating Hereditary Rare Diseases With In Vivo Precision Genetic Medicines (THRIVE)
Jan 9, 2026[Solicitation (Updated)] Treating Hereditary Rare Diseases With In Vivo Precision Genetic Medicines (THRIVE)
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