Toxicity evaluation of YC1 in hSULT1A1 and mSULT1A1 mice

Agency: HEALTH AND HUMAN SERVICES, DEPARTMENT OF
State: Maryland
Type of Government: Federal
FSC Category:
  • B - Special Studies and Analyses - Not R&D
NAICS Category:
  • 541380 - Testing Laboratories
Set Aside: No Set aside used
Posted Date: Aug 12, 2025
Due Date: Aug 18, 2025
Solicitation No: 75N95025Q00237
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Description

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Toxicity evaluation of YC1 in hSULT1A1 and mSULT1A1 mice
Active
Contract Opportunity
Notice ID
75N95025Q00237
Related Notice
Department/Ind. Agency
HEALTH AND HUMAN SERVICES, DEPARTMENT OF
Sub-tier
NATIONAL INSTITUTES OF HEALTH
Office
NATIONAL INSTITUTES OF HEALTH NIDA
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General Information
  • Contract Opportunity Type: Presolicitation (Original)
  • Original Published Date: Aug 12, 2025 06:55 am EDT
  • Original Response Date: Aug 18, 2025 12:00 pm EDT
  • Inactive Policy: 15 days after response date
  • Original Inactive Date: Sep 02, 2025
  • Initiative:
    • None
Classification
  • Original Set Aside: No Set aside used
  • Product Service Code: B504 - SPECIAL STUDIES/ANALYSIS- CHEMICAL/BIOLOGICAL
  • NAICS Code:
    • 541380 - Testing Laboratories and Services
  • Place of Performance:
    Rockville , MD 20850
    USA
Description

NCATS seeks to determine if YC1 which works with a unique mechanism of cytotoxicity

towards cancer cells that express SULT1A1. In doing so, NCATS shall establish the

therapeutic window for YC1. To that end NCATS requires head-to-head comparison on

YC1 in mice that have humanized SULT1A1 (custom mice available at

GemPharmaTech) and with mouse SULT1A1 (wild type).


Attachments/Links
Contact Information
Contracting Office Address
  • c/o 3WFN MSC 6012 301 N Stonestreet Ave
  • Bethesda , MD 20892
  • USA
Primary Point of Contact
Secondary Point of Contact
History
  • Aug 12, 2025 06:55 am EDTPresolicitation (Original)
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