Research Opportunity: DNA-Protein Epigenetic Chemistry Engineering (D-PECHE)

Agency: DEPT OF DEFENSE
State: Federal
Type of Government: Federal
FSC Category:
  • 66 - Instruments and Laboratory Equipment
NAICS Category:
  • 541990 - All Other Professional, Scientific, and Technical Services
Posted Date: May 18, 2026
Due Date: Jun 24, 2026
Solicitation No: DARPA-SN-26-67
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Contact information: Please Login to View Page
Bid Documents: Please Login to View Page

Description

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Research Opportunity: DNA-Protein Epigenetic Chemistry Engineering (D-PECHE)
Active
Contract Opportunity
Notice ID
DARPA-SN-26-67
Related Notice
Department/Ind. Agency
DEPT OF DEFENSE
Sub-tier
DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)
Office
DEF ADVANCED RESEARCH PROJECTS AGCY
General Information
  • Contract Opportunity Type: Special Notice (Updated)
  • Updated Published Date: May 18, 2026 10:07 am EDT
  • Original Published Date: May 06, 2026 02:57 pm EDT
  • Updated Response Date: Jun 24, 2026 04:00 pm EDT
  • Original Response Date: Jun 24, 2026 04:00 pm EDT
  • Inactive Policy: Manual
  • Updated Inactive Date: Jun 25, 2026
  • Original Inactive Date: Jun 25, 2026
  • Initiative:
    • None
Classification
  • Original Set Aside:
  • Product Service Code:
  • NAICS Code:
  • Place of Performance:
Description
UPDATE: The purpose of Amendment 1 to DARPA-SN-26-67, the DNA-Protein Epigenetic Chemistry Engineering (D-PECHE) Special Notice (SN), is to clarify submission instructions and deadlines.

The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals to demonstrate proof-of-concept for novel mechanisms for writing and erasing epigenetic base modifications in DNA. Mechanisms capable of modifying the epigenome offer new opportunities to control DNA-protein interactions and to study the functions and applications of rare or novel epigenetic modifications. This research opportunity will result in demonstrations of novel technologies to modify nucleic acids in vitro.
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Contact Information
Contracting Office Address
  • 675 NORTH RANDOLPH STREET
  • ARLINGTON , VA 222032114
  • USA
Primary Point of Contact
Secondary Point of Contact


History

Related Document

May 6, 2026[Special Notice (Original)] Research Opportunity: DNA-Protein Epigenetic Chemistry Engineering (D-PECHE)
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