: Liquid Chromatography–Mass Spectrometry System Maintenance and Service Agreement Renewal

Background Information: The mission of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is to conduct and support medical research and research training and to disseminate science-based information on diabetes and other endocrine and metabolic diseases; digestive diseases, nutritional disorders, and obesity; and kidney, urologic, and hematologic diseases, to improve people’s health and quality of life.

The Natural Products Chemistry Section of the Laboratory of Bioorganic Chemistry (LBC) conducts research focused on the discovery and development of novel antibiotics and antiviral compounds. Many of these molecules have the potential to become therapeutic agents that could significantly improve human health and support the mission of NIDDK. The laboratory routinely relies on an existing High-Performance Liquid Chromatography–Mass Spectrometry (HPLC-MS) system to identify, characterize, and confirm the structures of synthetic and natural compounds. The HPLC-MS system provides critical data for structural elucidation, molecular composition determination, rapid identification of known compounds, and compound characterization. Continued operation of this analytical system is essential to support ongoing research activities and the generation of data required for publication in peer-reviewed chemistry journals.