High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators (HUBBLE)

Agency: DEPT OF DEFENSE
State: Federal
Type of Government: Federal
FSC Category:
  • A - Research and development
NAICS Category:
  • 541714 - Research and Development in Biotechnology (except Nanobiotechnology)
Posted Date: Oct 28, 2026
Due Date: Nov 5, 2026
Solicitation No: DARPA-PA-27-01
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Contact information: Please Login to View Page
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Description

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High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators (HUBBLE)
Active
Contract Opportunity
Notice ID
DARPA-PA-27-01
Related Notice
Department/Ind. Agency
DEPT OF DEFENSE
Sub-tier
DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)
Office
DEF ADVANCED RESEARCH PROJECTS AGCY
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General Information View Changes
  • Contract Opportunity Type: Solicitation (Updated)
  • Updated Published Date: Oct 28, 2026 11:37 am EDT
  • Original Published Date: Oct 08, 2026 03:57 pm EDT
  • Updated Date Offers Due: Nov 05, 2026 03:00 pm EST
  • Original Date Offers Due: Nov 05, 2026 03:00 pm EST
  • Inactive Policy: Manual
  • Updated Inactive Date: Jan 10, 2027
  • Original Inactive Date: Jan 10, 2027
  • Initiative:
    • None
Classification
  • Original Set Aside:
  • Product Service Code: AC12 - NATIONAL DEFENSE R&D SERVICES; DEPARTMENT OF DEFENSE - MILITARY; APPLIED RESEARCH
  • NAICS Code:
    • 541714 - Research and Development in Biotechnology (except Nanobiotechnology)
  • Place of Performance:
Description View Changes
UPDATE: The purpose of Amendment 1 to DARPA-PA-27-01, the HUBBLE Program Announcement (PA), is to update Attachment B and the verbiage in Section 4.1.2 and Section 7.8 of the Program Announcement.

The Defense Advanced Research Projects Agency (DARPA) is soliciting proposals to develop an in-silico capability for mapping all protein-protein interactions. Utility of this capability will be demonstrated in identifying novel diagnostic and therapeutic targets within the interaction space underlying including traumatic brain injury.
Attachments/Links
Contact Information
Contracting Office Address
  • 675 NORTH RANDOLPH STREET
  • ARLINGTON , VA 222032114
  • USA
Primary Point of Contact
Secondary Point of Contact


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