Generative Optogenetics (GO)

Agency: DEPT OF DEFENSE
State: Federal
Type of Government: Federal
FSC Category:
  • A - Research and development
NAICS Category:
  • 541714 - Research and Development in Biotechnology (except Nanobiotechnology)
Posted Date: Dec 19, 2025
Due Date: Feb 26, 2026
Solicitation No: DARPA-PS-26-10
Original Source: Please Login to View Page
Contact information: Please Login to View Page
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Description

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Generative Optogenetics (GO)
Active
Contract Opportunity
Notice ID
DARPA-PS-26-10
Related Notice
Department/Ind. Agency
DEPT OF DEFENSE
Sub-tier
DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA)
Office
DEF ADVANCED RESEARCH PROJECTS AGCY
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General Information
  • Contract Opportunity Type: Solicitation (Original)
  • Original Published Date: Dec 19, 2025 05:07 pm EST
  • Original Date Offers Due: Feb 26, 2026 04:00 pm EST
  • Inactive Policy: Manual
  • Original Inactive Date: Mar 28, 2026
  • Initiative:
    • None
Classification
  • Original Set Aside:
  • Product Service Code: AC12 - NATIONAL DEFENSE R&D SERVICES; DEPARTMENT OF DEFENSE - MILITARY; APPLIED RESEARCH
  • NAICS Code:
    • 541714 - Research and Development in Biotechnology (except Nanobiotechnology)
  • Place of Performance:
Description
The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative concepts to design a protein complex that can be expressed in vivo (i.e., in a living cell) and responds to optical signals to synthesize a corresponding DNA or RNA sequence. This technology should enable massless transfer of genetic information to cells expressing the protein complex via a template-free mechanism that incorporates nucleotide bases in response to specific optical signals (e.g., different wavelengths of light). The GO program is focused on two main Research Objectives (ROs): (1) achieving the core capability of synthesizing DNA/RNA directly in living cells using optical signals, and (2) developing error mitigation methods that ensure high-fidelity nucleic acid synthesis. The acquisition process for GO will proceed through a two-stage process, starting with (1) written abstracts which will inform invitations to brief (2) an Oral Proposal Package (OPP) at DARPA.
Attachments/Links
Contact Information
Contracting Office Address
  • 675 NORTH RANDOLPH STREET
  • ARLINGTON , VA 222032114
  • USA
Primary Point of Contact
Secondary Point of Contact


History
  • Dec 19, 2025 05:07 pm ESTSolicitation (Original)
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