Custom Model Generation-3-5 Calb1-2A-Flp KI live mice

Agency: HEALTH AND HUMAN SERVICES, DEPARTMENT OF
State: Federal
Type of Government: Federal
FSC Category:
  • 88 - Live Animals
NAICS Category:
  • 112990 - All Other Animal Production
Posted Date: Nov 18, 2024
Due Date: Nov 22, 2024
Solicitation No: 25-001089
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Contact information: Please Login to View Page
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Description

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Custom Model Generation-3-5 Calb1-2A-Flp KI live mice
Active
Contract Opportunity
Notice ID
25-001089
Related Notice
Department/Ind. Agency
HEALTH AND HUMAN SERVICES, DEPARTMENT OF
Sub-tier
NATIONAL INSTITUTES OF HEALTH
Office
NATIONAL INSTITUTES OF HEALTH NIA
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General Information
  • Contract Opportunity Type: Sources Sought (Original)
  • Original Published Date: Nov 18, 2024 11:37 am EST
  • Original Response Date: Nov 22, 2024 11:59 am EST
  • Inactive Policy: 15 days after response date
  • Original Inactive Date: Dec 07, 2024
  • Initiative:
    • None
Classification
  • Original Set Aside:
  • Product Service Code: 8820 - LIVE ANIMALS, NOT RAISED FOR FOOD
  • NAICS Code:
    • 112990 - All Other Animal Production
  • Place of Performance:
Description

Statement of Need and Purpose: The purpose of this acquisition is to purchase the custom made Calb1-2A-Flp knock-in mice in support of research into Parkinson’s disease within the Laboratory of Neurogenetics (LNG).



Background Information and Objective:

The National Institute on Aging, Laboratory of Neurogenetics (LNG), required knock mice to understand the pathological basis of neurodegenerative diseases, primarily ALS, Parkinson's Disease and Alzheimer's Disease. The mice will be used to crossbreed with other mouse lines to investigate the connectivity and function of distinct neuronal subtypes implicated in Parkinson's disease and related disorders. These capabilities are essential to support research into Parkinson's disease within the LNG.



Salient characteristics and deliverables

All deliverables required under this contract shall be packaged, marked and shipped in accordance with Government specifications. At a minimum, all deliverables shall be marked with the contract number and provider name. The provider shall guarantee that all required materials shall be delivered in immediate usable and acceptable condition. Final deliverables:




  • Three-five (3-5) germline-transmitted, heterozygous F1 mice containing the desired knock-in, Calb1-2A-Flp.

  • Final report containing details of the targeting and genotyping strategies, as well as experimental results.


Attachments/Links
Contact Information
Contracting Office Address
  • 6001 EXECUTIVE BLVD., ROOM 5120
  • ROCKVILLE , MD 20852
  • USA
Primary Point of Contact
Secondary Point of Contact
History
  • Nov 18, 2024 11:37 am ESTSources Sought (Original)
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