CRO Services for Single-Cell Multiomics Profiling

Agency: HEALTH AND HUMAN SERVICES, DEPARTMENT OF
State: Maryland
Type of Government: Federal
FSC Category:
  • Q - Medical Services
NAICS Category:
  • 541714 - Research and Development in Biotechnology (except Nanobiotechnology)
Set Aside: Total Small Business Set-Aside (FAR 19.5)
Posted Date: Sep 4, 2025
Due Date: Sep 9, 2025
Solicitation No: 75N95025Q00238
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Description

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CRO Services for Single-Cell Multiomics Profiling
Active
Contract Opportunity
Notice ID
75N95025Q00238
Related Notice
Department/Ind. Agency
HEALTH AND HUMAN SERVICES, DEPARTMENT OF
Sub-tier
NATIONAL INSTITUTES OF HEALTH
Office
NATIONAL INSTITUTES OF HEALTH NIDA
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General Information
  • Contract Opportunity Type: Presolicitation (Original)
  • Original Published Date: Sep 04, 2025 10:57 am EDT
  • Original Response Date: Sep 09, 2025 11:00 am EDT
  • Inactive Policy: 15 days after response date
  • Original Inactive Date: Sep 24, 2025
  • Initiative:
    • None
Classification
  • Original Set Aside: Total Small Business Set-Aside (FAR 19.5)
  • Product Service Code: Q301 - REFERENCE LABORATORY TESTING
  • NAICS Code:
    • 541714 - Research and Development in Biotechnology (except Nanobiotechnology)
  • Place of Performance:
    MD 20850
    USA
Description

NCATS requires a contract research organization (CRO) to perform Human Discovery Panel (HDP) analysis to obtain single-cell multiomic data that shall inform NCATS on transcriptomic and proteomic alterations during inflammatory sensitization in human pluripotent stem cellderived sensory neurons (hPSC-SNs). Capable vendors must prepare and sequence a total of 33 samples (provided by NCATS), and will provide NCATS the data upon completion.

The Contractor shall provide a single-cell multi-nomics platform that allows combined single-cell RNA sequencing with DNA barcoded antibodies that target up to 325 distinct proteins for 33 sample hPSC-SNs under different inflammatory conditions.



Activities shall include the following:

MultiPro Human Discovery Panel; - Quantity 2.

MultiPro Human Enhanced Blocking Reagent; Quantity 8

Genomics Analysis Service; Quantity 1


Attachments/Links
Contact Information
Contracting Office Address
  • c/o 3WFN MSC 6012 301 N Stonestreet Ave
  • Bethesda , MD 20892
  • USA
Primary Point of Contact
Secondary Point of Contact
History
  • Sep 04, 2025 10:57 am EDTPresolicitation (Original)

Related Document

Aug 5, 2025[Sources Sought (Original)] Human Discovery Panel (HDP) analysis to obtain single cell multiomic data
Sep 19, 2025[Award Notice (Original)] CRO Services for Single-Cell Multiomics Profiling
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