Cap-dependent endonuclease inhibitors (CENis) - NHRC

Agency: DEPT OF DEFENSE
State: Texas
Type of Government: Federal
FSC Category:
  • A - Research and development
NAICS Category:
  • 541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
Set Aside: No Set aside used
Posted Date: May 26, 2026
Due Date: May 28, 2026
Solicitation No: N0018926QB059
Original Source: Please Login to View Page
Contact information: Please Login to View Page
Bid Documents: Please Login to View Page

Description

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Cap-dependent endonuclease inhibitors (CENis) - NHRC
Active
Contract Opportunity
Notice ID
N0018926QB059
Related Notice
Department/Ind. Agency
DEPT OF DEFENSE
Sub-tier
DEPT OF THE NAVY
Major Command
NAVSUP
Sub Command
NAVSUP GLOBAL LOGISTICS SUPPORT
Sub Command 2
NAVSUP FLC NORFOLK
Office
NAVSUP FLT LOG CTR NORFOLK
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General Information View Changes
  • Contract Opportunity Type: Combined Synopsis/Solicitation (Updated)
  • Updated Published Date: May 26, 2026 01:16 pm EDT
  • Original Published Date: May 15, 2026 02:47 pm EDT
  • Updated Date Offers Due: May 28, 2026 05:00 pm EDT
  • Original Date Offers Due: May 25, 2026 05:00 pm EDT
  • Inactive Policy: 15 days after date offers due
  • Updated Inactive Date: Jun 12, 2026
  • Original Inactive Date: Jun 09, 2026
  • Initiative:
    • None
Classification
  • Original Set Aside: No Set aside used
  • Product Service Code: AN42 - HEALTH R&D SERVICES; HEALTH CARE - OTHER; APPLIED RESEARCH
  • NAICS Code:
    • 541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
  • Place of Performance:
    Galveston , TX
    USA
Description

The preclinical development of Cap-dependent endonuclease inhibitors (CENi), a class of small molecules, as broad-spectrum antiviral therapeutics. The scope of this project includes all activities required to select lead CENi candidates, including in vitro and in vivo efficacy studies and characterization and optimization of lead compounds. This includes Research Support expertise regarding the preclinical development of cap-dependent endonuclease inhibitors (CENis) with viruses that require biosafety level 4 (BSL-4) containment to support the Naval Medical Research Command in Fort Detrick, MD. This work will be performed over a 36-month period.


Attachments/Links
Contact Information
Contracting Office Address
  • ATTENTION CODE 301 1968 GILBERT STREET SUITE 600
  • NORFOLK , VA 23511-3392
  • USA
Primary Point of Contact
Secondary Point of Contact
History

Related Document

May 15, 2026[Combined Synopsis/Solicitation (Original)] Cap-dependent endonuclease inhibitors (CENis) - NHRC
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