Agentic AI-EnableD CardioVascular CAre TransfOrmation (ADVOCATE) Innovative Solutions Opening (ISO)
| Agency: | HEALTH AND HUMAN SERVICES, DEPARTMENT OF |
|---|---|
| State: | District of Columbia |
| Type of Government: | Federal |
| FSC Category: |
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| NAICS Category: |
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| Posted Date: | Feb 23, 2026 |
| Due Date: | Apr 1, 2026 |
| Solicitation No: | ARPA-H-SOL-26-142 |
| Original Source: | Please Login to View Page |
| Contact information: | Please Login to View Page |
| Bid Documents: | Please Login to View Page |
Description
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- Contract Opportunity Type: Solicitation (Updated)
- Updated Published Date: Feb 23, 2026 11:19 am EST
- Original Published Date: Jan 13, 2026 11:59 am EST
- Updated Date Offers Due: Apr 01, 2026 05:00 pm EDT
- Original Date Offers Due: Apr 01, 2026 05:00 pm EDT
- Inactive Policy: 15 days after date offers due
- Updated Inactive Date: Apr 16, 2026
- Original Inactive Date: Apr 16, 2026
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Initiative:
- None
- Original Set Aside:
- Product Service Code: AN13 - HEALTH R&D SERVICES; HEALTH CARE SERVICES; EXPERIMENTAL DEVELOPMENT
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NAICS Code:
- 541714 - Research and Development in Biotechnology (except Nanobiotechnology)
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Place of Performance:
Washington , DC 20005USA
February 23, 2026
ADVOCATE ISO, ARPA-H-SOL-26-142, Amendment 02:
The purpose of ARPA-H-SOL-26-142, Amendment 02 is to revise the following sections as shown in the highlighted text:
- Table of Contents
- TA1: CVD Agent – Reliable Agentic Care Management under Section 1.2.1 Technical Areas (TA)
- Phase 2 (15 months) – Scalability Studies under Section 1.2.2 Program Structure & Timeline
- Section 3. Submission Information
- Section 4.1 Solution Summary Review Process
- Section 4.2 Full Proposal Evaluation Criteria
- Section 4.2.1 Criteria 1: Overall Scientific and Technical Merit
- Section 4.4 Handling of Sensitive Information
See attached ADVOCATE ISO, ARPA-H-SOL-26-142, Amendment 02.
__________________________
February 5, 2026
ADVOCATE ISO, ARPA-H-SOL-26-142, Amendment 01:
The purpose of ARPA-H-SOL-26-142, Amendment 01 is as follows:
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Make a correction to Table 7 – Performer Collaboration Expectations under Section 1.2.5 Performer Collaboration Expectations (See highlighted text).
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Revise the last paragraph under Section 5.1 Proposing Teams (See highlighted text) to read: “Proposers interested in submitting a proposal for TA3 cannot submit a proposal for TA1 and TA2 in any capacity (e.g. prime, subperformer, or multi-party team). TA3 proposers can only submit one proposal for the TA3 work outlined in this solicitation.”
- Update the first sentence of Section 6.2 Organization Conflicts of Interest (OCI) (See highlighted text) to read: “The proposer, through submission of a proposal, is required to identify and disclose all facts relevant to any potential OCI involving the proposer, its organization, and/or any proposed team member (i.e. proposed sub-performer, consultant).”
See attached ADVOCATE ISO, ARPA-H-SOL-26-142, Amendment 01.
___________________
January 13, 2026
The Advanced Research Projects Agency for Health (ARPA-H) Agentic AI-Enabled Cardiovascular Care Transformation (ADVOCATE) program will enable the development of an Agentic system that delivers autonomous and semi-autonomous clinical care directly to patients with cardiovascular disease (CVD).
Interested parties are invited to review the attached ADVOCATE Innovative Solutions Opening (ISO) ARPA-H -SOL-26-142.
For detailed information regarding the ADVOCATE Proposers' Day, review Special Notice (SN) ARPA-H-SN-26-139.
- 1301 K Street NW Suite 1200 West
- Washington , DC 20005
- USA
- SEE DESCRIPTION SECTION
- do_not_use_this_email_address@arpa-h.gov
- Feb 23, 2026 11:19 am ESTSolicitation (Updated)
- Feb 05, 2026 02:03 pm EST Solicitation (Updated)
- Jan 13, 2026 11:59 am EST Solicitation (Original)
Related Document
| Jan 13, 2026 | [Solicitation (Original)] Agentic AI-EnableD CardioVascular CAre TransfOrmation (ADVOCATE) Innovative Solutions Opening (ISO) |
| Feb 5, 2026 | [Solicitation (Updated)] Agentic AI-EnableD CardioVascular CAre TransfOrmation (ADVOCATE) Innovative Solutions Opening (ISO) |
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