Specialized Toxicological Analyses Open Date: 07/08/08 02:30 PM Agency Requisition Number: 582-8-80187 NOTE: You will need to download all of the following files for specifications and other required document, including a HUB subcontracting plan(if required). Help: Right Click to and choose "save file as" or "save target as" to your computer. -Package 1 size: 696131 (in bytes) Type: Specification Format: Acrobat PDF Files

This contract is for multiple projects relating to performing advanced toxicological analyses for a chemical-specific toxicity assessment. TCEQ staff is developing chemical-specific Development Support Documents that outline the hazard assessment and dose-response processes used to derive chemical-specific Effects Screening Levels (ESLs), Reference Values (ReV), and Unit Risk Factors (URFs). The toxicity values are developed using RG-442 Guidelines to Develop Effects Screening Levels, Reference Values, and Unit Risk Factors (TCEQ 2006) (hereafter referred as RG-442 ESL Guidelines). The RG-442 ESL Guidelines can be found at: http://www.tceq.state.tx.us/implementation/tox/esl/guidelines/about.html. ESLs are chemical-specific air concentrations set to protect human health and welfare. Short-term ESLs are based on data concerning acute health effects, odor potential, and vegetative effects, while long-term ESLs are generally based on data concerning chronic noncarcinogenic or carcinogenic health effects, or both. ESLs are used in the evaluation of air permit applications as well as proposed rules and regulation (e.g. Permits by Rule). ReVs and URFs, used as the basis of ESLs, are used in the evaluation of air monitoring data and in the development of Protective Concentration Levels for remediation sites. Although the majority of advanced toxicological analyses will be used for toxicity assessments via the inhalation route, it is possible that toxicity assessments involving an ingestion or dermal route of exposure may need to be evaluated.

Agency: TEXAS COMMISSION ON ENVIRONMENTAL QUALITY (582)

Previous Price Paid: N/A

Deliver Date: 10/01/08

Solicitation type: 21 Days or more for solicitation notice

NIGP Commodity Code(s):

	Class-Item: 961 - 48
	Class-Item: 961 - 74

Contact Information:
Contact Name:	Wendy Cox
Email:	wcox@tceq.state.tx.us
Address:	PO Box 13087 MC-182
	Austin, TX 78711-3087
Phone:	(512) 239-5555
Fax:	(512) 239-0823

Upload Date: 2008-06-10 13:51:06.917 Updated date: 2008-06-10 13:52:05.583