| 66 -- Purchase of Partec Volumetric Flow Cytometer |
| Program Summary |
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| Description |
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General Information
| Document Type: |
Presolicitation Notice |
| Solicitation Number: |
Reference-Number-NCI-80019-MM |
| Posted Date: |
Dec 17, 2007 |
| Original Response Date: |
Dec 31, 2007 |
| Current Response Date: |
Dec 31, 2007 |
| Original Archive Date: |
Jan 15, 2008 |
| Current Archive Date: |
Jan 15, 2008 |
| Classification Code: |
66 -- Instruments & laboratory equipment |
| Naics Code: |
334516 -- Analytical Laboratory Instrument Manufacturing |
Contracting Office Address
Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 6120 Executive Blvd. EPS Suite 600, Rockville, MD, 20852, UNITED STATES
Description
The National Cancer Institute (NCI) plans to procure on a sole source basis for a Partec Volumetric Flow Cytometer with the following components: Partec CyFlow ML, Parameters, 20mW Blue Laser, and 20mW Yellow Laser with Gene Check Applied Technologies, 1629 Blue Spruce Dr., Suite 106, Ft. Collins, Colorado, 80524.
This acquisition will be processed under FAR Part 12 Acquisition for Commercial Items and will be made pursuant to the authority in FAR 13.106-(b)(1) and 13.501-(a)(1) to use simplified procedures for commercial acquisitions. The North American Industry Classification System Code is 334516 and the business size standard is 500 employees.
The following salient characteristics apply to the Partec Volumetric Flow Cytometer:
- 488nm solid-state laser and a 561nm solid-state laser for broad spectrum
- Capable of having up to 4 lasers and a mercury arc lamp for future upgrade
- Photomultiplier tubes for detecting 6 colors of fluorescence and be upgradeable to 13 colors of fluorescence
- High-quality objective with a high-numerical aperture for fluorescent light collection and capable of immersion gel coupling
- Volumetric absolute cell counting capability
- 16-bit analog to digital conversion
- Capable of up to 32,768 channel resolution
- Capable of trigger on any parameter or combination of parameters
- Parallel signal processing for each parameter to allow for high-speed data acquisition at speeds up to 100,000 cells per second
- Precise, syringe-controlled sample input for regulating sample flow rates between 0 and 50 uL per second
- Automated, N-color, software, spectral compensation
- Multi-parameter color-gating
- Color CCD camera for viewing the sample and laser intercept
- Occupy less than 2 square feet of bench space (excluding computer)
- Upgradeable to provide automated input from microtiter plates
- Upgradeable to provide automated loading of sample tubes
The Gene Regulation Section of the Laboratory of Pathology, CCR, NCI is charged
with studying the regulation and de-regulation of the expression of the c-myc oncogene. Such de-regulation is among the most common molecular abnormalities in human cancer, and contributes to the deaths of an estimated 70,000 Americans each year. Therefore, it is clearly of benefit to the Section, the NCI and the NIH, and hence to the government, to facilitate studies that will enable re-regulation of c-myc in cancer. Recent work from the Gene Regulation Section has indicated that cell-to-cell variation in c-myc maybe more important in the pathogenesis of cancer than the average (bulk) levels in tumors. Flow cytometry is the premier and best way to measure molecules at the level of single cells. Such measurements of c-myc as obtained through the utilization of the instrument herein requested will provide information about the molecular processes regulating and de-regulating c-myc that would be completely unobtainable otherwise. Thus purchase and operation of this instrument therefore will advance the governmental mission of the Gene Regulation Section, Laboratory of Pathology, CCR, NCI to promote the health and well-being of all Americans.
This is not a solicitation for competitive quotations. However, if any interested party believes they can meet the above requirement, they may submit a statement of capabilities. All information furnished shall be in writing and must contain sufficient detail to allow the NCI to determine if it can meet the above unique specifications described herein. An original and one copy of the capability statement must be received in the NCI contracting office by 1:00 PM ET on December 31, 2007. All questions must be in writing and can be faxed (301) 402-4513 or emailed to Melissa Marino, Contract Specialist at marinome@mail.nih.gov. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. In order to receive an award, contractors must have valid registration and certification in the Central Contractor Registration (CCR) www.ccr.gov and the Online Representations and Certifications Applications (ORCA), http://orca.bpn.gov. No collect calls will be accepted. Please reference NCI-80019-MM on all correspondence.
Point of Contact
Melissa Marino, Contract Specialist, Phone 301-402-4509, Fax 301-402-4513, Email marinome@mail.nih.gov - Renita Smith, Contract Specialist, Phone 301-496-8612, Fax 301-480-0241, Email rs442i@nih.gov
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