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L -- Patent Application Services for: SINGLE MOLECULE MASS SPECTROMETRY IN SOLUTION USING A SOLITARY NANOPORE; Docket # 08-003
Program Summary
Title: L -- Patent Application Services for: SINGLE MOLECULE MASS SPECTROMETRY IN SOLUTION USING A SOLITARY NANOPORE; Docket # 08-003
GovCB Opps ID : ADP12047167100000756
Document Type: Combine Solicitation
FSC Code: L - Technical Representative Services
NAICS Code: 541199 - All Other Legal Services
Set Aside: Total Small Business
Solicitation No.: SB134108RQ0125
Source: http://www1.fbo.gov/spg/DOC/NIST/AcAsD/SB134108RQ0125/Combine%20Synopsis%5FSolicitation....
Place of
Performance:
Address: NIST (Gaithersburg, MD) Postal Code: 20899 Country: UNITED STATES
Posted Date:
Mar 04, 2008
Last Update: Mar 07, 2008
Due Date: Mar 12, 2008

Description
General Information

Document Type: Combine Solicitation
Solicitation Number: SB134108RQ0125
Posted Date: Mar 04, 2008
Original Response Date: Mar 12, 2008
Current Response Date: Mar 12, 2008
Original Archive Date: Mar 19, 2008
Current Archive Date: Mar 19, 2008
Classification Code: L -- Technical representative services
Set Aside: Total Small Business
Naics Code: 541199 -- All Other Legal Services
Contracting Office Address
Department of Commerce, National Institute of Standards and Technology (NIST), Acquisition Management Division, 100 Bureau Drive, Building 301, Room B129, Mail Stop 1640, Gaithersburg, MD, 20899-1640, UNITED STATES
Description
This is a combined synopsis/solicitation for commercial services prepared in accordance with the format in FAR Parts 12 and 13, as supplemental with additional information included in this notice.

This announcement constitutes the only solicitation, quotes are being requested and a separate written solicitation will not be issued.

Solicitation Number SB134108RQ0125 is issued as a request for quotation. The North American Industry Classification Code (NAICS) is 541199.     The NIST Technology Services Laboratory has a requirement for preparation, submission and prosecution of a Non-Provisional Patent Applications and an Accelerated Patent Application for the following National Institute of Standards and Technology (NIST) Invention. Independently and not as an agent of the Government, the Contractor shall provide services in accordance with the Statement of Work (SOW), Preparation, Submission and Prosecution of a Non-Provisional Patent Application for the following National Institute of Standards and Technology (NIST) Invention:

SINGLE MOLECULE MASS SPECTROMETER IN SOLUTION USING A SOLITARY NANOPORE

I. Invention Abstract

The invention of the single molecule mass spectrometer permits measurement of an electrical current passing through a stable nanopore under an applied voltage, while partial occlusion of the pore occurs by molecules that reduce the electrical current.     Reduction of the electrical current occurs because the nanopore's size is commensurate with that of the molecule. The nanopores may be modified to interact selectively with chosen targets. Specific averaging methods are used that, in effect, act as signal averaging of the individual currents and allows these current levels to be assigned to molecules of different sizes. In addition, the kinetics of the chemical interactions of the analytes within a given nanopore can be found once the current levels are assigned. The set of current levels together with the kineticsprovide a novel two-dimensional method of analysis for charged and uncharged molecules in solution.

A more complete description of the invention, its development and reduction to practice is presented in the attached article entitled "Single-Molecule Mass Spectrometer in Solution Using a Solita Nanopore," published in the Proceedings of the National Academy of Sciences (PNAS) of the United States of America, May 15,2007, volume 104, number. 20, pages 8207-8211.

II. Background
      
In carrying out its responsibilities to promote technology transfer under the Stevenson-Wydler Act of 1980(as amended by the Federal Technology Transfer Act (FTTA) of 1986) the National Institute of Standards and Technology (NIST) through its Office of Technology Partnerships (OTP) often seeks patent protection for inventions.       These inventions are developed at NIST laboratories during the course of scientific and technical activities carried on in support of the NIST mission. The decision to file a non-provisional patent application for a specific invention is made when NIST determines that a patent for the invention will significantly enhance the technology transfer/commercialization attractiveness of the invention to the private, for-profit sector.

III. Scope of Work
      
The work to be delivered under this SOW by the contractor shall include all necessary supporting research, preparation, submission and prosecution of a non-provisional U.S. patent application for the above referenced NIST invention.

IV. Task

Task 1 - Conduct all supporting research that, in the professional judgment of the Contractor, is necessary to prepare a non-provisional U. S. patent application. This shall include but not be limited to the following:

       a. Review of all technical material submitted by the NIST inventor concerning the        invention with the inventor(s).

b. Render an opinion concerning the patentability of the invention.

Task 2 - Prepare the patent application and all necessary supporting documentation in preparation for filing at the U. S. Patent and Trademark Office (USPTO).     This will be accomplished with final approval on patent application content rendered by the first NIST inventor as named on the application.

Task 3 - File non-provisional patent application with the USPTO. This shall include but not be limited to the following:
      
       a. Contractor shall file the patent application with all pertinent ink drawings and diagrams        with transmittal papers with the US PTO along with an executed Declaration and Power        of Attorney, and shall report the completion of this action to the NIST Technical        Information Contact (TIC).

       b. Contractor shall request an immediate Publication by the USPTO after the effective date of application submission patent award.

       c. Contractor shall request the Information Disclosure Statement when the application is        filed.

       d. Contractor shall send to the NIST TIC an electronic copy of the invention?s non-       provisional patent application as filed with the US PTO immediately after the        application?s filing.

Task 3 - Election and preparation of Response to Restriction Requirements

       a. Contractor shall provide an Analysis Letter to accompany the Response to First Office Action to include receipt, review, reporting, preparation and filing of response and reporting.
b. Contractor shall provide an Analysis Letter to accompany the Response to Second Office Action and all subsequent office actions to include Final Office Action, to include receipt, review, reporting, preparation and filing of response and reporting.

Task 4 - Electronic Copy of Claims

a.       Contractor shall provide an Electronic Copy of Claims as added, deleted and/or modified in Response to Office Actions after Response is filed with the US PTO.

b.       Contractor shall provide the filing of Drawings Amended according to the Allowed Claims.

c.       Contractor shall provide the Response to Notice of Filing Missing Parts of Application.

d.       Contractor shall receipt, review and provide to the NIST TIC Reporting of Notice of Allowability.

e.       Contractor shall review the file wrapper for any outstanding items and resolve any outstanding issues with the USPTO.

f.       Contractor shall conduct a US PTO Examiners interview.     The interviews can be conducted in person or by telephone.

V. Deliverables

The highly variable nature of the patent process and the large, diverse number of necessary interim work products often required to support the preparation, submission and prosecution of a patent application, make it difficult to specify the exact number, type and content or these work products or to prepare a schedule for their production and delivery.

NIST understands that decisions to prepare these interim products are within the realm of a patent attorney?s professional practice and dictated by what the attorney believes to be the ?best professional practice? in the client?s interest. No time schedule or list of work products can possibly anticipate all of the contingencies that can arise during the patent prosecution that require such products. Nevertheless, the following deliverable products have been identified for production and delivery to the intended recipients during this contract:

V.1-Non-Provisional Patent Application suitable for timely submission to the USPTO        with all required supporting forms, declarations and other documentation.

V.2-All submissions, e.g., amendments to the application, prepared by the Contractor in        response to first, second and subsequent office actions taken during the patent        prosecution by the USPTO.

V.3-All supporting drawings and diagrams intended for filing with the Non-Provisional        Patent Application or in response to subsequent office actions.

V.4 Appellate documents files after Final Office Action.

V.5 The Contractor?s case file for the entire patent prosecution, to include all attorney        correspondence with the US PTO.

VI. Period of Performance

       The period of performance for this contract is five (5) years from the effective date of        award, but may be extended as necessary by NIST for an additional five (5) one-year options for prosecuting this non-provisional patent.

A firm-fixed-price quotation for the SOW requirements that traces back to the proposed SOW, and work breakdown structure
      
VII. Government Furnished Property
      
All technical documentation to include drawings, data, invention descriptions, articles,     and technical and administrative memoranda concerning the invention that may be necessary input to the preparation and prosecution of the patent application.

VIII. Exhibits and Attachments
       None      

Period of Performance: The period of performance for this contract is a base period of five (5) years with five (5) one year options.           Price Quote - Please submit a firm fully burdened hourly rate and number of hours for this Patent Application work.           The Government will provide technical documentation to include drawings, data, invention descriptions, articles, and technical and administrative memoranda concerning the invention may be provided by the Government for necessary input to the preparation and prosecution of the patent application.          

TIC: The Technical Information Contact is: to be determined, National Institute of Standards and Technology.

Place of Performance: NIST, Gaithersburg, Maryland 20899.                      

The resulting purchase order shall be negotiated on a firm fixed price basis.                       The award shall be made on a best value basis. The best value evaluation factors while relatively equal are listed in order of importance, include the following: 1) Approach - The likelihood of effectively meeting the requirements; 2) Past Performance - The relevance and quality of prior performance; and 3) Price - The amount, realism and consistency of the evaluated price. The evaluation shall be based on use of the adjectival scheme as follows: Outstanding (O) - Conspicuously striking in eminence; Excellent (E) - Very good of its kind; eminently good, superior or first class; Good (G) - Beneficial and worthwhile; sound and valid; Adequate (A) - Reasonably sufficient and suitable; Marginal (M) - Minimally suitable at the lower limit; Unsatisfactory (U) - Not acceptable, not adequate to carry out. The solicitation document and incorporated clauses are those in effect through Federal Acquisition Circular Number 2005-20. The provisions and clauses may be downloaded at http://www.acqnet.gov.far.

The following provisions and clauses shall apply to this solicitation.
FAR 52.212-1, Instructions to Offerors - Commercial, applies to this acquisition and there is no addenda to this provision; FAR 52,212-2, Evaluation - Commercial Items. The Government shall award a purchase order resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The following factors shall be used to evaluate offers: (i) approach, (ii) past performance, (iii) price; FAR 52.212-3, Offeror Representations and Certifications - Commercial Items, applies to this acquisition and there is no addenda to this provision; FAR 52.212-4, Contract Terms and Conditions - Commercial Items, applies to this acquisition and there is no addenda to this provision; FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items, applies to this acquisition; FAR 52.204-9, Personal Identity Verification of Contractor Personnel; FAR 52.227-14, Rights in Data - General; 52.217-8 Option to Extend Services;     52.217-9                       Option to Extend the Term of the Contract and other appropriate clauses as needed. All interested contractors must be actively registered in the Central Contractor Registration (CCR) at the CCR website www.ccr.gov and must provide a completed copy of the Offeror Representations and Certifications.

Interested contractors are invited to review the above Statement of Work NIST-Patent Application Services for SINGLE MOLECULE MASS SPECTROMETRY IN SOLUTION USING A SOLITARY NANOPORE; Docket # 08-003


An electronic response to be received no later than March 12, 2008 addressed to George Ralis, Contract Specialist, National Institute of Standards and Technology, 100 Bureau Drive, Stop 1640Gaithersburg, Maryland 20899-1640, george.ralis@nist.gov.

Contractors must submit a complete response. Responses that are not substantially complete will be returned. Offers of partial performance shall be rejected. An original and four copies shall be submitted as well as an electronic version in MS Word or Adobe Acrobat. The electronic version shall be in the form of an email with attachments. A one page letter shall transmit the quotation signed by an individual authorized to commit the organization. Each response shall be on 8 1/2-inch x 11-inch paper, in a commercially standard font, not smaller than a size 12 font. The response shall be secured by simple stapling and shall not contain elaborate binding. Each page in the response shall be separately numbered. A page of paper printed on both sides is considered two pages. The quote shall include the letter of transmittal, shall be limited to twelve (12) single sided pages or less. Submit quotes arranged in three sections as follows.: Section I - Approach, which includes identification and qualifications of relevant personnel and technical management approach; Section II - Past Performance for relevant experience which describes at least three                       (3) relevant projects performed in the last three years and quality of performance; Section III - Price, firm fixed price for the required technical consulting services. Each firm fixed price shall include sufficient data to allow the Government to determine the amount, realism and consistency of the fixed price. Award shall be made to the responsible contractor that offers the best value to the Government. The Government shall not be liable for any costs incurred in response to this request.                       The Government reserves the right to make a single award, multiple awards, or no award as a result of this RFQ.                       It is the responsibility of the contractor to confirm NIST's receipt of quote.


Point of Contact
George Ralis, Business Specialist, Phone 301-975-6312, Email george.ralis@nist.gov - Mario Checchia, Contract Specialist/Contracting Officer, Phone 301-975-8407, Fax 301-975-2541, Email mario.checchia@nist.gov
Point of Contact
George Ralis, Business Specialist, Phone 301-975-6312, Email george.ralis@nist.gov - Mario Checchia, Contract Specialist/Contracting Officer, Phone 301-975-8407, Fax 301-975-2541, Email mario.checchia@nist.gov
Place of Performance
Address: NIST (Gaithersburg, MD)
Postal Code: 20899
Country: UNITED STATES




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